The 'Laboratory Biosafety Manual - Fourth Edition' is a comprehensive guide published by the World Health Organization, focusing on ensuring safety in laboratory environments. It provides detailed strategies for biosafety, including methods for cleaning, disinfection, waste management, and inactivation of biological samples. The manual aims to prevent exposure to biological agents and ensure the safe handling of hazardous materials. It targets professionals in laboratory settings, offering guidelines and best practices to maintain safety and mitigate risks associated with biological agents. With contributions from experts globally, it serves as an essential resource for laboratory safety management.