This publication by the World Health Organization provides an extensive overview of bacterial vaccines currently in clinical and preclinical development. It emphasizes their role in combating antimicrobial resistance (AMR) by reducing the incidence of both resistant and susceptible infections, thereby decreasing antibiotic consumption. The report categorizes vaccine candidates into various groups based on their development stage and feasibility, focusing on pathogens listed in the 2017 WHO Bacterial Priority Pathogens List. It highlights advancements in vaccine technology that enable the targeting of previously challenging pathogens and identifies 61 candidates in active clinical development and 94 in preclinical development. The book serves as a valuable resource for healthcare professionals, researchers, and policymakers interested in the development and implementation of vaccines to control AMR globally.