"Hobo John" is an English blues enthusiast on a pilgrimage to present-day Mississippi. One night in Clarksdale he meets the mysterious Fat Man, who offers him the chance to see the real blues of the 1930s. Unable to refuse, Hobo John embarks on a journey through the afterlife in the company of Travellin' Man, an old blues guitarist who shows him the sights, sounds and everyday life in the Mississippi Delta. Along the way, the Englishman discovers the harsh realities behind his romantic notion of the music he loves and the true price of the deal that he has made.