This companion book to the HBO Documentary Films series explores the cutting-edge research on Alzheimer's disease that is creating new hope for the future. Alzheimer's disease is the second most-feared illness in America, following cancer. It affects as many as 5 million Americans, a number that could soar to 16 million by 2050. It is estimated that, unless effective preventions are discovered, 10 million baby boomers will eventually develop this irreversible and devastating brain disorder. Until recently, medical news on Alzheimer's disease was not comforting. But in the past few years, advances in many scientific areas -- from diagnostic imaging to genetic analysis -- have led to an explosion of knowledge with implications for treatment and prevention. This is an exciting time of discovery in Alzheimer's research. Through The Alzheimer's Project film series, HBO Documentary Films illuminates the vital breakthroughs occurring in the field. One of the central films in this series, Momentum in Science, brings us inside the laboratories and clinics of the nation's top scientists and physicians who are clearing the path to a deeper understanding of Alzheimer's disease. By capturing the exhilaration of these scientists and casting light on their groundbreaking discoveries, the film seeks to bring a wider understanding of the disease and new hope for future treatment. This book offers an even closer look at the advances of this scientific frontier. It investigates the complex cascade of events that occurs inside the brain when someone has Alzheimer's disease and shows how scientists are working to interrupt this process and ultimately prevent the disease. In accessible prose, it examines specific evidence of momentous progress, from the triumphant discovery of the unique role of the beta-amyloid and tau proteins, to the use of PET scans to track changes in the brain and the analyses of cerebrospinal fluid to identify biomarkers that will help us predict who will develop the disease in the future. It also looks at current drug development and at what we can do as individuals to potentially reduce our risk of developing the disease. The Alzheimer's Project: Momentum in Science is a fascinating story of scientific discovery that shows what recent breakthroughs might mean for improving our chances of remaining cognitively vital throughout a long life.

本書は、忘却の病に対し科学が「希望」の光を投じる様を克明に描いた一冊です。脳内の異変を生命の壮大なドラマとして捉え直す視座に、知的好奇心が強く揺さぶられます。未知へ挑む科学者たちの情熱と、絶望を知識で凌駕しようとする知性の軌跡は、まさに人間賛歌そのものと言えるでしょう。 HBOの映像が現場の熱狂を伝える「動」の表現であるならば、本書は現象の深層をじっくりと思索させる「静」の役割を担っています。映像が喚起する感情を、テキストならではの精密な論理が補完することで、病への恐怖は克服すべき対象へと昇華されます。メディアを横断するからこそ得られる、この立体的な理解と希望の感触をぜひ体感してください。