This report shows how improving gender mainstreaming via the Greater Mekong Subregion Economic Cooperation Program Strategic Framework 2030 (GMS-2030) can bolster inclusivity and ensure women benefit equally from regional cooperation initiatives. Highlighting common barriers hindering women’s participation, it explains how the Gender Strategy Implementation Plan (GSIP) 2025–2030 aims to develop innovative new ways to mainstream gender, explicitly address gender barriers, and tackle pervasive social norms. It details how proposals including setting up a Task Force on Gender, building a knowledge base, and integrating gender equality into GMS-2030’s core operations will help meet the GSIP goals.