Adult-Onset Progeria had become a world-wide problem. Numerous vaccines had been developed to stem its harm, yet no one knew how it spread or why. However, after one man, a struggling Secret Service Agent was a attacked by a mob of infected, some took notice. Notice because he not only survived the attack, when no one else had even survived a single bite, but he recovered and thrived. Then something else unexpected happened. Patient Zero actually started to get younger and heal at an incredible rate. Now, different factions all wanted him all to the them selves. Because not only was the cure to Adult-Onset Progeria in his blood, so was the cure to everything, as well as the fountain of youth. Now is twin brother, with a small group of volunteers were going to break him out of a secured facility and find the cure for themselves, or die trying.

ハントレーが描く本作は、老いという人類普遍の恐怖を「成人発症型早老症」という災厄に昇華させた、極上のサスペンスです。単なるバイオホラーに留まらず、若返りの力を得た「患者第零号」を巡る血塗られた狂騒は、人間の飽くなき生への執着と倫理の崩壊を鮮烈に浮き彫りにします。救世主か、あるいは究極の資源か。極限状態で試される兄弟の絆が、読む者の魂を激しく揺さぶります。 映像化作品では、感染者が迫る圧倒的な視覚的恐怖とアクションの躍動感が補完されていますが、原作の真髄は主人公の孤独な内面描写と緻密な心理戦にあります。文字から立ち上る「死と再生」の冷徹な熱量は、映像では削ぎ落とされがちな情報の深みを与えてくれます。両者を併せて享受することで、加速する世界と逆行する生命のコントラストが、より鮮明な叙事詩として完結するのです。