This is an open access book. Disruption becomes a social phenomenon that occurs in society. In the disruption era, education will face many challenges. One of the challenge in education is how to improve students’ skills in global competition in society 5.0. Competition does not only involve competition between humans and humans, but also competition between humans and a robotic-based work system by utilizing artificial intelligence. Many experts predict that there will be around 130 professions from new sectors that will present and will replace old professions. However, some of universities are disrupted by various kinds of technological innovations in education. There are several disruptions that can be categorized in the world of education, namely, Disruption of Generations, Disruption of Technology, and Disruption of the Industrial Revolution 4.0. The current generation tends to be different from the previous generation because the current generation prefers collaborative learning through interactive learning media, compared to learning that is carried out in class. Technological disruption is related to the existence of technological innovations (e.g. open educational resources) in the education, such as ruangguru, chem academies and learning gaming that change the educational setting. Classrooms may not be needed too much, teachers as facilitators and learning places more emphasis on collaborative and social activities. The disruption of the industrial revolution 4.0 disrupts existing activities, because they are no longer relevant and have been replaced by artificial intelligence or robots. Not only repetitive work, but also analytical work will also be disrupted, such as analysts, consultants, lawyers, accountants and translators. Advances in machine learning, big data analytics, and artificial intelligence, internet of things, virtual reality, and augmented reality will shift from jobs that are repetitive jobs to creative jobs. Education needs to respond and adapt to this phenomenon, because after all a shift in globalization is a necessity. FITK Alma Ata University and SEAMEAO Regional Open Learning Centre will convene the 1st International Collaboration Conference on Education. The theme of this conference is Future Education in the Disruption Era. This conference will declare by virtually when all experts, policy makers, educators, and other stakeholders to share best practice and discuss on how we as global citizens response to the education challenge in the disruption era.