The Routledge International Handbook of Research Security examines research security – the act of protecting and securing university research and teaching in the name of national security – through a multidisciplinary and comparative lens. In this volume, contributors explore theoretical, domestic, international, and practical pursuits of research security across the globe. Over six sections, the handbook covers topics ranging from the composition of research security programs and frameworks to the futures of research security and academic freedom. Academic experiences of espionage, foreign interference, intelligence, and counter-intelligence operations are discussed to provide international and comparative perspectives on research security. In so doing, this book shows the tensions of finding a middle ground between the needs of national security and the global research enterprise. Offering a balanced and structured perspective of research security from both academics and practitioners, this handbook is a unique resource for graduate students in fields such as law, security studies, international relations, and strategic management. It will also interest higher education professionals such as research managers and security directors.