The good times of pre-AIDS Las Vegas is suddenly interrupted for attorney and private investigator Reggie Darr; the love of his life, Carla; his muscle-bound male friends; and his unusual collection of roommates. A serial killer stalks the Strip, threatening tourism and everyday life for Las Vegas residents. Together with the FBI and Las Vegas Metropolitan Police Department, Reggie devises an unconventional plan to identify and capture or kill the pervert who threatens the usual din of the Las Vegas casinos. Accomplishing this will require great sacrifice on the part of Reggie, his friends, and a couple hundred citizens of Las Vegas.