Rare afflictions of the scrotum and scrotal contents manifest with nonspecific symptoms and signs which simulate the manifestations of more common afflictions and lesions of the scrotum and scrotal contents. In view of these, without a high index of suspicion, an examining clinician could initially miss the diagnosis of the lesion or there may be a delay in the establishment of the correct diagnosis. In view of the rarity of some scrotal afflictions of the scrotum and scrotal contents, these rare lesions have not been covered in detail in most books of surgery, urology, and medicine. Medical or surgical misdiagnosis causes psychological problems to a number of individual patients who worry about the unknown cause of their afflictions. In order to ensure that clinicians all over the world are up to date with rare afflictions of the scrotum and scrotal contents, some miscellaneous rare afflictions have been discussed in detail in the book to ensure that the articles in the book are suitable reference material for all clinicians in all areas of the world.