Tropical cyclones (TCs) can cause billions of dollars in property damage and up to thousands of life losses globally every year. In order to mitigate these socioeconomic impacts, scientists have strived in developing sophisticated numerical modeling systems to provide better tools for research and forecast communities, especially in those coastal countries and regions that are impacted substantially by TCs in the past several decades. Recently, several accelerated efforts were made by several research and operational centers after tremendous property and life losses by landfall TCs in the North Atlantic, the Western North Pacific, and the North Indian Ocean basins. The modeling systems in regional forecast centers are planning to upgrade to the next generation or make significant advances through those accelerations. In this Research Topic, the goal is to document the latest developments, physics improvements, data assimilation, holistic forecast systems, and their applications. Themes include the significant model new features, high-resolution physics for TC applications, data assimilation methodology and observational data impacts, forecast experiments, model verification and validation. Studies on the role of physical processes associated with the boundary layer, convection and microphysics, radiation, land surface processes, air-sea-wave processes are encouraged. The model evaluations including quantitative precipitation forecasts and tools, and products for TC research and forecasts are welcome as well. Novel studies and latest model developments having a research to operation (R2O) transition possibility will be considered for publication. The ultimate goal is to exchange research ideas, advances, and understanding across the global TC communities. We welcome Original Research and Review Articles from development, observational, numerical modeling, and forecasting perspectives on TCs. Articles can include, but are not limited to, the following topics: • Model development; • TC vortex initialization algorithm; • High-resolution physics for TC; • Air-sea-wave interactions; • Model tracking and intensity verification; • Data assimilation methods; • Observational data impacts; • Model evaluation tools; • Model evaluation comparison products for research and forecasts; and • Novel studies based on new findings and methodology.