Never before have we been presented with the prospect of redesigning business at scale to create a more sustainable future for our planet and the people who inhabit it. As we pass the midpoint of the Sustainable Development Goals (2015–2030), the world has changed. There is not only more progress and policy but also more disagreement on the way forward. The bottom line is that the shared goals developed in 2015 will not be met, global warming will likely exceed targets, and the collective challenge will be left to a new generation. The book is organized as a series of business challenges and key questions that enable a transition from making legacy companies more carbon and waste efficient, to operating in fundamentally new ways. The vast majority of the new infrastructure the world will need by 2050 still needs to be built. Those challenges will not be solved by legacy companies working to protect their market position in the face of a changing world. The book offers a chapter-by-chapter guide to enable new leaders to turn challenges into opportunities.