In 1977 a 34 year-old navigator on a US transport aircraft was incapacitated and a peer reviewed paper was published in the journal, Clinical Toxicology. Disturbance in the mental and neuromuscular function of aircraft flight personnel by any influence is of obvious concern and significance. This report documents the incapacitation of an aircraft navigator during flight. This situation resulted from an inhalation exposure to aerosolized or vaporized synthetic lubricating oil. Further investigation into the potential hazards from inhalation of synthetic oil fumes that are generated by these circumstances is definitely warranted.The call for proper investigations into the potential hazards of inhaling synthetic oil fumes was never addressed, just covered up with misinformation. Thirty years later, commercial aircraft continue to fly with no contaminated air detection systems or filtration systems to prevent passengers and crews from breathing hazardous and neurotoxic chemicals.