Dr. Phillips has assembled well-published authors on optimizing patient outcomes in those living with HIV and AIDS. The clinical reviews in this issue will provide nurses with the current clinical information they need to incorporate best practices into their patient care and manageement. Articles are devoted to the following topics: Exercise and Positive Living in HIV/AIDS; Managing Other Chronic Illnesses in PLWHAl; Nutritional Issues and Positive Living in HIV/AIDS; Spiritual Dimensions/Resilience; Positive Thinking in HIV/AIDS; Health Promotion in HIV/AIDS; Mental Health in HIV/AIDS; Promoting Cardiovascular Health in PLWHA; Pharmacological Considerations in HIV/AIDS; and Sleep Disturbances Associated with HIV/AIDS.