Cody Rexell is back, and still doesn't give a F*ck! His adventures this time take him to the heat of the Mexican jungle. Barely escaping with his life from a remote village of bloodthirsty cannibals, Rexel is determined to go back and retrieve an item of great importance that was taken from him. When a face from the past betrays Rexell and threatens to send him back to the government who are still searching for him, he reluctantly agrees to help with a covert mission to locate a drug baron who has gone missing in the jungle. As the group embark on what should be a routine mission, events unfold that puts the lives of everyone at risk and forces Rexell to revert to his uniquely violent methods to ensure those under his supervision survive.