Adrian, our hero from Class of the Dead, must traverse through a zombie apocalypse to find Alexandria; the young girl that has fallen in love with him, not knowing if she and the other survivors from Class of the Dead are even alive or not. Along the way, he meets new friends and deadly enemies that are more dangerous than the ravenous dead that infest the cities that lay between him and Alexandria. Also a father returns home from a hunting trip to search of his sons in hopes they are still alive.