Critically analyzing the specific security threat posed by COVID-19 to global society, the contributors to this book offer a comprehensive and critical examination of global challenges and responses while suggesting more balanced and nuanced approaches to handling these security impacts. The COVID-19 pandemic brought about a huge challenge to health security across the globe. Several countries were pushed into lockdown repeatedly to prevent the spread of infection. The global economy has seen a major slowdown and disruption of supply chains around the world. There have also been major implications from changes to traditional security systems as well as diverse societal change even down to aspects of daily life. The chapters in this book show that progressive initiatives have expended a mixture of soft and hard response strategies that include understanding, containing, fighting, and preventing COVID-19. They look at major sectors including defense, trade, health, and bioterrorism among others. In doing so, they highlight the best practices used around the world to minimize the threat posed by COVID-19’s impact. A vital resource for security studies scholars and policymakers.